Clinical Compliance Managed By Student Health Services

Clinical Hepatitis B

Hepatitis B is a liver disease caused by the Hepatitis B virus (HBV). It ranges in severity from a mild illness, lasting a few weeks (acute), to a serious long-term (chronic) illness that can lead to liver disease or liver cancer.

A vaccine to prevent Hepatitis B was developed and first became available in 1981. A blood test for the Hepatitis B surface antibody can prove immunity after the vaccine series is completed.

To become compliant for Hepatitis B you must first decide between the two choices below:

Have blood drawn and tested for immunity

Depending on your age or if you have ever worked in the health care field you may have been immunized for Hepatitis B

You may have been immunized for Hepatitis B if:

  • You were in middle or high school in California in 1997 or later

  • You have worked in healthcare

  • If either of the above is true you need to have your blood drawn and tested for immunity. This blood test is called a Hepatitis B surface antibody titer.

Start Hepatitis B vaccine series

If you know that you have never been immunized for Hepatitis B then you must start the vaccine series. If you need Hep A as well as B you can choose to have the Twinrix vaccine series(Hep A & B combo shot). Both series are given as:

  • Dose #1 now, #2 in 1 month, #3 approximately 5 months after #2

  • One month after the #3 vaccine have blood drawn and tested for immunity. This blood test is called a Hepatitis B surface antibody titer.(You do not need to titer for Hep A)

Ultimately, you must have a positive or immune titer for Hepatitis B antibodies in order to be compliant

If your titer comes back negative, non-immune or equivocal you will need to receive the 3 shot vaccine series and re-titer one month after the last shot.

If titer remains negative, non-immune or equivocal after two full shot series, you are considered an Non-Responder. Please go to Non-Responder page.

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